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Structural and Energetic Insights Into the Interaction of Niacin With the GPR109A Receptor

The transmembrane G-protein coupled receptor GPR109A has been previously shown to function as a receptor for niacin in mediating antilipolytic effects. Although administration of high doses of niacin has shown beneficial effects on lipid metabolism, however, it is often accompanied by disturbing sid...

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Detalles Bibliográficos
Autores principales: Adepu, Kiran Kumar, Kachhap, Sangita, Anishkin, Andriy, Chintapalli, Sree V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637708/
https://www.ncbi.nlm.nih.gov/pubmed/34866904
http://dx.doi.org/10.1177/11779322211056122