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Can the SARS-CoV-2 Spike Protein Bind Integrins Independent of the RGD Sequence?
The RGD motif in the Severe Acute Syndrome Coronavirus 2 (SARS-CoV-2) spike protein has been predicted to bind RGD-recognizing integrins. Recent studies have shown that the spike protein does, indeed, interact with α(V)β(3) and α(5)β(1) integrins, both of which bind to RGD-containing ligands. Howeve...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637727/ https://www.ncbi.nlm.nih.gov/pubmed/34869067 http://dx.doi.org/10.3389/fcimb.2021.765300 |