Sirtuin-3 Protects Cochlear Hair Cells Against Noise-Induced Damage via the Superoxide Dismutase 2/Reactive Oxygen Species Signaling Pathway

Mitochondrial oxidative stress is involved in hair cell damage caused by noise-induced hearing loss (NIHL). Sirtuin-3 (SIRT3) plays an important role in hair cell survival by regulating mitochondrial function; however, the role of SIRT3 in NIHL is unknown. In this study, we used 3-TYP to inhibit SIR...

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Detalles Bibliográficos
Autores principales: Liang, Wenqi, Zhao, Chunli, Chen, Zhongrui, Yang, Zijing, Liu, Ke, Gong, Shusheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637754/
https://www.ncbi.nlm.nih.gov/pubmed/34869361
http://dx.doi.org/10.3389/fcell.2021.766512

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637754/
https://www.ncbi.nlm.nih.gov/pubmed/34869361
http://dx.doi.org/10.3389/fcell.2021.766512

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