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Pharmacological Inhibition of HMGB1 Prevents Muscle Wasting

Background: Cachexia is a multifactorial disorder characterized by weight loss and muscle wasting, making up for about 20% of cancer-related death. However, there are no effective drugs to combat cachexia at present. Methods: In this study, the effect of CT26 exosomes on C2C12 myotubes was observed....

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Detalles Bibliográficos
Autores principales: Li, Lu, Liu, Huiquan, Tao, Weili, Wen, Su, Fu, Xiaofen, Yu, Shiying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637759/
https://www.ncbi.nlm.nih.gov/pubmed/34867338
http://dx.doi.org/10.3389/fphar.2021.731386