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Insights into auto-S-fatty acylation: targets, druggability, and inhibitors

Posttranslational S-fatty acylation (or S-palmitoylation) modulates protein localization and functions, and has been implicated in neurological, metabolic, and infectious diseases, and cancers. Auto-S-fatty acylation involves reactive cysteine residues in the proteins which directly react with fatty...

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Detalles Bibliográficos
Autores principales: Hu, Lu, Tao, Zhipeng, Wu, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637764/
https://www.ncbi.nlm.nih.gov/pubmed/34977571
http://dx.doi.org/10.1039/d1cb00115a