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Biodegradable self-assembly micelles significantly enhanced the solubility, biological stability and in vivo antitumor efficacy of Hexylselen

Glutaminolysis inhibitors have shown early promise in cancer therapeutics. Specifically, kidney-type glutaminase (KGA) has been a long-standing anti-tumor drug target; KGA allosteric inhibitors have attracted great attention due to their superior enzyme specificity and good drug safety profiles. How...

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Detalles Bibliográficos
Autores principales: Fang, Jinzhang, Chen, Zhao, Song, Jun, Li, Jinxiu, Han, Yunying, Hou, Wei, Wang, Wenxi, Ruan, Benfang H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637765/
https://www.ncbi.nlm.nih.gov/pubmed/34977582
http://dx.doi.org/10.1039/d1cb00089f