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Multimodal Imaging Technology Effectively Monitors HER2 Expression in Tumors Using Trastuzumab-Coupled Organic Nanoparticles in Patient-Derived Xenograft Mice Models

Trastuzumab is a monoclonal antibody targeting human epidermal growth factor 2 (HER2), which has been successfully used in the treatment of patients with breast cancer and gastric cancer; however, problems concerning its cardiotoxicity, drug resistance, and unpredictable efficacy still remain. Herei...

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Detalles Bibliográficos
Autores principales: Wen, Li, Xia, Lei, Guo, Xiaoyi, Huang, Hai-Feng, Wang, Feng, Yang, Xian-teng, Yang, Zhi, Zhu, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637767/
https://www.ncbi.nlm.nih.gov/pubmed/34869025
http://dx.doi.org/10.3389/fonc.2021.778728