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Circulating CitH3 Is a Reliable Diagnostic and Prognostic Biomarker of Septic Patients in Acute Pancreatitis

PURPOSE: Acute pancreatitis (AP) is an inflammatory disease. AP starts with sterile inflammation and is often complicated with critical local or systemic infection or sepsis in severe cases. Septic AP activates peptidyl arginine deiminase (PAD) and citrullinates histone H3 (CitH3), leading to neutro...

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Detalles Bibliográficos
Autores principales: Pan, Baihong, Li, Yaozhen, Liu, Yu, Wang, Wei, Huang, Gengwen, Ouyang, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637845/
https://www.ncbi.nlm.nih.gov/pubmed/34868018
http://dx.doi.org/10.3389/fimmu.2021.766391