Activation of a G protein-coupled receptor through indirect antibody-mediated tethering of ligands

Antibodies raised against many cell surface proteins, including G protein-coupled receptors, remain important tools for their functional characterization. By linking antibodies to ligands for cell surface proteins, such adducts can be targeted to the surface of a cell type of choice. Site-specific f...

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Detalles Bibliográficos
Autores principales: Cheloha, Ross W., Fischer, Fabian A., Gardella, Thomas J., Ploegh, Hidde L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637866/
https://www.ncbi.nlm.nih.gov/pubmed/34977584
http://dx.doi.org/10.1039/d1cb00118c

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637866/
https://www.ncbi.nlm.nih.gov/pubmed/34977584
http://dx.doi.org/10.1039/d1cb00118c

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