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Activation of a G protein-coupled receptor through indirect antibody-mediated tethering of ligands
Antibodies raised against many cell surface proteins, including G protein-coupled receptors, remain important tools for their functional characterization. By linking antibodies to ligands for cell surface proteins, such adducts can be targeted to the surface of a cell type of choice. Site-specific f...
Autores principales: | Cheloha, Ross W., Fischer, Fabian A., Gardella, Thomas J., Ploegh, Hidde L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
RSC
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8637866/ https://www.ncbi.nlm.nih.gov/pubmed/34977584 http://dx.doi.org/10.1039/d1cb00118c |
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