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Rare and potentially pathogenic variants in hydroxycarboxylic acid receptor genes identified in breast cancer cases
BACKGROUND: Three genes clustered together on chromosome 12 comprise a group of hydroxycarboxylic acid receptors (HCARs): HCAR1, HCAR2, and HCAR3. These paralogous genes encode different G-protein coupled receptors responsible for detecting glycolytic metabolites and controlling fatty acid oxidation...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8638184/ https://www.ncbi.nlm.nih.gov/pubmed/34852802 http://dx.doi.org/10.1186/s12920-021-01126-3 |