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Rare and potentially pathogenic variants in hydroxycarboxylic acid receptor genes identified in breast cancer cases

BACKGROUND: Three genes clustered together on chromosome 12 comprise a group of hydroxycarboxylic acid receptors (HCARs): HCAR1, HCAR2, and HCAR3. These paralogous genes encode different G-protein coupled receptors responsible for detecting glycolytic metabolites and controlling fatty acid oxidation...

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Detalles Bibliográficos
Autores principales:	McGuire Sams, Cierla, Shepp, Kasey, Pugh, Jada, Bishop, Madison R., Merner, Nancy D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8638184/ https://www.ncbi.nlm.nih.gov/pubmed/34852802 http://dx.doi.org/10.1186/s12920-021-01126-3

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