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Placental SARS-CoV-2 distribution correlates with level of tissue oxygenation in COVID-19-associated necrotizing histiocytic intervillositis/perivillous fibrin deposition

INTRODUCTION: Recent evidence supports the – rare – occurrence of vertical transplacental SARS-CoV-2 transmission. We previously determined that placental expression of angiotensin-converting enzyme 2 (ACE2), the SARS-CoV-2 receptor, and associated viral cell entry regulators is upregulated by hypox...

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Detalles Bibliográficos
Autores principales: Mao, Quanfu, Chu, Sharon, Shapiro, Svetlana, Young, Lawrence, Russo, Melissa, De Paepe, Monique E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8638245/
https://www.ncbi.nlm.nih.gov/pubmed/34929459
http://dx.doi.org/10.1016/j.placenta.2021.12.002