Chemokine CCL2 prevents opioid-induced inhibition of nociceptive synaptic transmission in spinal cord dorsal horn

BACKGROUND: Opioid analgesics remain widely used for pain treatment despite the related serious side effects. Some of those, such as opioid tolerance and opioid-induced hyperalgesia may be at least partially due to modulation of opioid receptors (OR) function at nociceptive synapses in the spinal co...

Descripción completa

Detalles Bibliográficos
Autores principales: Heles, Mario, Mrozkova, Petra, Sulcova, Dominika, Adamek, Pavel, Spicarova, Diana, Palecek, Jiri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8638248/
https://www.ncbi.nlm.nih.gov/pubmed/34857006
http://dx.doi.org/10.1186/s12974-021-02335-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8638248/
https://www.ncbi.nlm.nih.gov/pubmed/34857006
http://dx.doi.org/10.1186/s12974-021-02335-4

Ejemplares similares