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Chemokine CCL2 prevents opioid-induced inhibition of nociceptive synaptic transmission in spinal cord dorsal horn

BACKGROUND: Opioid analgesics remain widely used for pain treatment despite the related serious side effects. Some of those, such as opioid tolerance and opioid-induced hyperalgesia may be at least partially due to modulation of opioid receptors (OR) function at nociceptive synapses in the spinal co...

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Detalles Bibliográficos
Autores principales:	Heles, Mario, Mrozkova, Petra, Sulcova, Dominika, Adamek, Pavel, Spicarova, Diana, Palecek, Jiri
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8638248/ https://www.ncbi.nlm.nih.gov/pubmed/34857006 http://dx.doi.org/10.1186/s12974-021-02335-4

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