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Exosomal microRNA-107 reverses chemotherapeutic drug resistance of gastric cancer cells through HMGA2/mTOR/P-gp pathway

BACKGROUND: RNA cargo in exosomes, especially microRNAs (miRNAs), play an important role in the chemotherapy drug resistance of human cancers. However, the role and mechanism of exosomal miR-107 on multidrug resistance of gastric cancer cells was still not clear. In this study, we sought to explore...

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Detalles Bibliográficos
Autores principales: Jiang, Lu, Zhang, Yan, Guo, Linghui, Liu, Chaoyang, Wang, Pan, Ren, Weihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8638432/
https://www.ncbi.nlm.nih.gov/pubmed/34856955
http://dx.doi.org/10.1186/s12885-021-09020-y