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Exosomal microRNA-107 reverses chemotherapeutic drug resistance of gastric cancer cells through HMGA2/mTOR/P-gp pathway
BACKGROUND: RNA cargo in exosomes, especially microRNAs (miRNAs), play an important role in the chemotherapy drug resistance of human cancers. However, the role and mechanism of exosomal miR-107 on multidrug resistance of gastric cancer cells was still not clear. In this study, we sought to explore...
Autores principales: | Jiang, Lu, Zhang, Yan, Guo, Linghui, Liu, Chaoyang, Wang, Pan, Ren, Weihong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8638432/ https://www.ncbi.nlm.nih.gov/pubmed/34856955 http://dx.doi.org/10.1186/s12885-021-09020-y |
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