High-dose drug heat map analysis for drug safety and efficacy in multi-spheroid brain normal cells and GBM patient-derived cells

To test the safety and efficacy of drugs via a high does drug heat map, a multi-spheroids array chip was developed by adopting a micropillar and microwell structure. In the chip, patient-derived cells were encapsulated in alginate and grown to maturity for more than 7 days to form cancer multi-spher...

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Detalles Bibliográficos
Autores principales: Lee, Sang-Yun, Teng, Yvonne, Son, Miseol, Ku, Bosung, Moon, Ho Sang, Tergaonkar, Vinay, Chow, Pierce Kah-Hoe, Lee, Dong Woo, Nam, Do-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8638871/
https://www.ncbi.nlm.nih.gov/pubmed/34855773
http://dx.doi.org/10.1371/journal.pone.0251998

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8638871/
https://www.ncbi.nlm.nih.gov/pubmed/34855773
http://dx.doi.org/10.1371/journal.pone.0251998

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