Comparison of TCF4 repeat expansion length in corneal endothelium and leukocytes of patients with Fuchs endothelial corneal dystrophy

Expansion of CTG trinucleotide repeats (TNR) in the transcription factor 4 (TCF4) gene is highly associated with Fuchs Endothelial Corneal Dystrophy (FECD). Due to limitations in the availability of DNA from diseased corneal endothelium, sizing of CTG repeats in FECD patients has typically been dete...

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Detalles Bibliográficos
Autores principales: Wieben, Eric D., Aleff, Ross A., Rinkoski, Tommy A., Baratz, Keith H., Basu, Shubham, Patel, Sanjay V., Maguire, Leo J., Fautsch, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8638873/
https://www.ncbi.nlm.nih.gov/pubmed/34855896
http://dx.doi.org/10.1371/journal.pone.0260837

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8638873/
https://www.ncbi.nlm.nih.gov/pubmed/34855896
http://dx.doi.org/10.1371/journal.pone.0260837

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