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7, 8-Dihydroxyflavone, a TrkB receptor agonist, provides minimal protection against retinal vascular damage during oxygen-induced ischemic retinopathy

Retinopathy of prematurity (ROP) is one of the main causes of blindness in children worldwide. Brain-derived neurotrophic factor (BDNF) and its receptor, tropomyosin-related kinase B (TrkB), play critical protective roles in the development and function of neurons and vasculature. Lack of BDNF expre...

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Detalles Bibliográficos
Autores principales: Zaitoun, Ismail S., Song, Yong-Seok, Suscha, Andrew, El Ragaby, Mohamed, Sorenson, Christine M., Sheibani, Nader
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8638941/
https://www.ncbi.nlm.nih.gov/pubmed/34855884
http://dx.doi.org/10.1371/journal.pone.0260793