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REST/NRSF drives homeostatic plasticity of inhibitory synapses in a target-dependent fashion

The repressor-element 1-silencing transcription/neuron-restrictive silencer factor (REST/NRSF) controls hundreds of neuron-specific genes. We showed that REST/NRSF downregulates glutamatergic transmission in response to hyperactivity, thus contributing to neuronal homeostasis. However, whether GABAe...

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Detalles Bibliográficos
Autores principales: Prestigio, Cosimo, Ferrante, Daniele, Marte, Antonella, Romei, Alessandra, Lignani, Gabriele, Onofri, Franco, Valente, Pierluigi, Benfenati, Fabio, Baldelli, Pietro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639147/
https://www.ncbi.nlm.nih.gov/pubmed/34855580
http://dx.doi.org/10.7554/eLife.69058