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Late adolescence mortality in mice with brain-specific deletion of the volume-regulated anion channel subunit LRRC8A

The leucine-rich repeat-containing family 8 member A (LRRC8A) is an essential subunit of the volume-regulated anion channel (VRAC). VRAC is critical for cell volume control, but its broader physiological functions remain under investigation. Recent studies in the field indicate that Lrrc8a disruptio...

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Detalles Bibliográficos
Autores principales: Wilson, Corinne S., Dohare, Preeti, Orbeta, Shaina, Nalwalk, Julia W., Huang, Yunfei, Ferland, Russell J., Sah, Rajan, Scimemi, Annalisa, Mongin, Alexander A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639177/
https://www.ncbi.nlm.nih.gov/pubmed/34469026
http://dx.doi.org/10.1096/fj.202002745R