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Hypoxia Upregulates NOTCH3 Signaling Pathway to Promote Endothelial-Mesenchymal Transition in Pulmonary Artery Endothelial Cells

BACKGROUND: To investigate the effect of hypoxia on pulmonary artery endothelial cells and the role of NOTCH3 in endothelial-mesenchymal transition (EnMT) and to provide a research model for pulmonary disease and explain the pathogenesis of the pulmonary disease. METHODS: Pulmonary artery endothelia...

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Detalles Bibliográficos
Autores principales: Wang, Li-Le, Zhu, Xiao-Li, Han, Shu-Hua, Xu, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639273/
https://www.ncbi.nlm.nih.gov/pubmed/34868328
http://dx.doi.org/10.1155/2021/1525619