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Hydrophobicity-tuned anion responsiveness underlies endosomolytic cargo delivery mediated by amphipathic vehicle peptides

Peptide conformation can change subject to environment cues. This concept also applies to many cationic amphipathic peptides (CAPs) known to have cell membrane lytic or penetrative activities. Well-conditioned CAPs can match the properties of the target membrane to support their intended biological...

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Detalles Bibliográficos
Autores principales: Chen, Xiaolong, Liu, Hanjie, Li, Ang, Ji, Shuangshuang, Fei, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639468/
https://www.ncbi.nlm.nih.gov/pubmed/34736897
http://dx.doi.org/10.1016/j.jbc.2021.101364