α-Synuclein Induces the GSK-3-Mediated Phosphorylation and Degradation of NURR1 and Loss of Dopaminergic Hallmarks

In Parkinson’s disease, the dysfunction of the dopaminergic nigrostriatal tract involves the loss of function of dopaminergic neurons of the substantia nigra pars compacta followed by death of these neurons. The functional recovery of these neurons requires a deep knowledge of the molecules that mai...

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Detalles Bibliográficos
Autores principales: García-Yagüe, Ángel Juan, Lastres-Becker, Isabel, Stefanis, Leonidas, Vassilatis, Demetrios K., Cuadrado, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639559/
https://www.ncbi.nlm.nih.gov/pubmed/34609698
http://dx.doi.org/10.1007/s12035-021-02558-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639559/
https://www.ncbi.nlm.nih.gov/pubmed/34609698
http://dx.doi.org/10.1007/s12035-021-02558-9

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