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α-Synuclein Induces the GSK-3-Mediated Phosphorylation and Degradation of NURR1 and Loss of Dopaminergic Hallmarks
In Parkinson’s disease, the dysfunction of the dopaminergic nigrostriatal tract involves the loss of function of dopaminergic neurons of the substantia nigra pars compacta followed by death of these neurons. The functional recovery of these neurons requires a deep knowledge of the molecules that mai...
Autores principales: | García-Yagüe, Ángel Juan, Lastres-Becker, Isabel, Stefanis, Leonidas, Vassilatis, Demetrios K., Cuadrado, Antonio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639559/ https://www.ncbi.nlm.nih.gov/pubmed/34609698 http://dx.doi.org/10.1007/s12035-021-02558-9 |
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