The N-Formyl Peptide Receptor 2 (FPR2) Agonist MR-39 Improves Ex Vivo and In Vivo Amyloid Beta (1–42)-Induced Neuroinflammation in Mouse Models of Alzheimer’s Disease

The major histopathological hallmarks of Alzheimer’s disease (AD) include β-amyloid (Aβ) plaques, neurofibrillary tangles, and neuronal loss. Aβ 1–42 (Aβ(1-42)) has been shown to induce neurotoxicity and secretion of proinflammatory mediators that potentiate neurotoxicity. Proinflammatory and neurot...

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Detalles Bibliográficos
Autores principales: Trojan, Ewa, Tylek, Kinga, Schröder, Nicole, Kahl, Iris, Brandenburg, Lars-Ove, Mastromarino, Margherita, Leopoldo, Marcello, Basta-Kaim, Agnieszka, Lacivita, Enza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639560/
https://www.ncbi.nlm.nih.gov/pubmed/34468933
http://dx.doi.org/10.1007/s12035-021-02543-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639560/
https://www.ncbi.nlm.nih.gov/pubmed/34468933
http://dx.doi.org/10.1007/s12035-021-02543-2

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