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Hypercholesterolemia and 27-Hydroxycholesterol Increase S100A8 and RAGE Expression in the Brain: a Link Between Cholesterol, Alarmins, and Neurodegeneration
Alterations in cholesterol metabolism in the brain have a major role in the physiology of Alzheimer’s disease (AD). Oxysterols are cholesterol metabolites with multiple implications in memory functions and in neurodegeneration. Previous studies have shown detrimental effects of cholesterol metabolit...
Autores principales: | Loera-Valencia, Raúl, Ismail, Muhammad-Al-Mustafa, Goikolea, Julen, Lodeiro, Maria, Mateos, Laura, Björkhem, Ingemar, Puerta, Elena, Romão, Mariana A., Gomes, Cláudio M., Merino-Serrais, Paula, Maioli, Silvia, Cedazo-Minguez, Angel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639576/ https://www.ncbi.nlm.nih.gov/pubmed/34449045 http://dx.doi.org/10.1007/s12035-021-02521-8 |
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