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Arhgap22 Disruption Leads to RAC1 Hyperactivity Affecting Hippocampal Glutamatergic Synapses and Cognition in Mice

Rho GTPases are a class of G-proteins involved in several aspects of cellular biology, including the regulation of actin cytoskeleton. The most studied members of this family are RHOA and RAC1 that act in concert to regulate actin dynamics. Recently, Rho GTPases gained much attention as synaptic reg...

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Detalles Bibliográficos
Autores principales: Longatti, Anna, Ponzoni, Luisa, Moretto, Edoardo, Giansante, Giorgia, Lattuada, Norma, Colombo, Maria Nicol, Francolini, Maura, Sala, Mariaelvina, Murru, Luca, Passafaro, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639580/
https://www.ncbi.nlm.nih.gov/pubmed/34455539
http://dx.doi.org/10.1007/s12035-021-02502-x