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The Impact of the Combined Administration of 1MeTIQ and MK-801 on Cell Viability, Oxidative Stress Markers, and Glutamate Release in the Rat Hippocampus

MK-801, as an N-methyl-D-aspartate (NMDA) receptor inhibitor, causes elevation in glutamate release, which may lead to an increase in excitotoxicity, oxidative stress and, consequently, cell death. 1-Methyl-1,2,3,4-tetrahydroisoquinoline (1MeTIQ) shows antioxidant activity. The aim of the present st...

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Detalles Bibliográficos
Autores principales: Wąsik, Agnieszka, Białoń, Magdalena, Jantas, Danuta, Żarnowska, Marcelina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639582/
https://www.ncbi.nlm.nih.gov/pubmed/34665405
http://dx.doi.org/10.1007/s12640-021-00428-9