Mechanism of Cellular Formation and In Vivo Seeding Effects of Hexameric β-Amyloid Assemblies

The β-amyloid peptide (Aβ) is found as amyloid fibrils in senile plaques, a typical hallmark of Alzheimer’s disease (AD). However, intermediate soluble oligomers of Aβ are now recognized as initiators of the pathogenic cascade leading to AD. Studies using recombinant Aβ have shown that hexameric Aβ...

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Detalles Bibliográficos
Autores principales: Vrancx, Céline, Vadukul, Devkee M., Suelves, Nuria, Contino, Sabrina, D’Auria, Ludovic, Perrin, Florian, van Pesch, Vincent, Hanseeuw, Bernard, Quinton, Loïc, Kienlen-Campard, Pascal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639606/
https://www.ncbi.nlm.nih.gov/pubmed/34608607
http://dx.doi.org/10.1007/s12035-021-02567-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639606/
https://www.ncbi.nlm.nih.gov/pubmed/34608607
http://dx.doi.org/10.1007/s12035-021-02567-8

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