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The pivotal role of the NLRC4 inflammasome in neuroinflammation after intracerebral hemorrhage in rats

The NLRC4 inflammasome, a member of the nucleotide-binding and oligomerization domain-like receptor (NLR) family, amplifies inflammation by facilitating the processing of caspase-1, interleukin (IL)–1β, and IL-18. We explored whether NLRC4 knockdown alleviated inflammatory injury following intracere...

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Detalles Bibliográficos
Autores principales: Gan, Hui, Zhang, Li, Chen, Hui, Xiao, Han, Wang, Lu, Zhai, Xuan, Jiang, Ning, Liang, Ping, Zheng, Shuyue, Zhao, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639719/
https://www.ncbi.nlm.nih.gov/pubmed/34848837
http://dx.doi.org/10.1038/s12276-021-00702-y