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Secreted frizzled related-protein 2 (Sfrp2) deficiency decreases adult skeletal stem cell function in mice

In a previous transcriptomic study of human bone marrow stromal cells (BMSCs, also known as bone marrow-derived “mesenchymal stem cells”), SFRP2 was highly over-represented in a subset of multipotent BMSCs (skeletal stem cells, SSCs), which recreate a bone/marrow organ in an in vivo ectopic bone for...

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Detalles Bibliográficos
Autores principales: de Castro, Luis Fernandez, Sworder, Brian J., Mui, Byron, Futrega, Kathryn, Berendsen, Agnes, Phillips, Matthew D., Burbach, Nathan J., Cherman, Natasha, Kuznetsov, Sergei, Gabet, Yankel, Holmbeck, Kenn, Robey, Pamela G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639730/
https://www.ncbi.nlm.nih.gov/pubmed/34857734
http://dx.doi.org/10.1038/s41413-021-00169-7