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Dietary excess regulates absorption and surface of gut epithelium through intestinal PPARα

Intestinal surface changes in size and function, but what propels these alterations and what are their metabolic consequences is unknown. Here we report that the food amount is a positive determinant of the gut surface area contributing to an increased absorptive function, reversible by reducing dai...

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Detalles Bibliográficos
Autores principales: Stojanović, Ozren, Altirriba, Jordi, Rigo, Dorothée, Spiljar, Martina, Evrard, Emilien, Roska, Benedek, Fabbiano, Salvatore, Zamboni, Nicola, Maechler, Pierre, Rohner-Jeanrenaud, Françoise, Trajkovski, Mirko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639731/
https://www.ncbi.nlm.nih.gov/pubmed/34857752
http://dx.doi.org/10.1038/s41467-021-27133-7