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Directed-evolution of translation system for efficient unnatural amino acids incorporation and generalizable synthetic auxotroph construction
Site-specific incorporation of unnatural amino acids (UAAs) with similar incorporation efficiency to that of natural amino acids (NAAs) and low background activity is extremely valuable for efficient synthesis of proteins with diverse new chemical functions and design of various synthetic auxotrophs...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639764/ https://www.ncbi.nlm.nih.gov/pubmed/34857769 http://dx.doi.org/10.1038/s41467-021-27399-x |