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Directed-evolution of translation system for efficient unnatural amino acids incorporation and generalizable synthetic auxotroph construction

Site-specific incorporation of unnatural amino acids (UAAs) with similar incorporation efficiency to that of natural amino acids (NAAs) and low background activity is extremely valuable for efficient synthesis of proteins with diverse new chemical functions and design of various synthetic auxotrophs...

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Detalles Bibliográficos
Autores principales: Zhao, Hongxia, Ding, Wenlong, Zang, Jia, Yang, Yang, Liu, Chao, Hu, Linzhen, Chen, Yulin, Liu, Guanglong, Fang, Yu, Yuan, Ying, Lin, Shixian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639764/
https://www.ncbi.nlm.nih.gov/pubmed/34857769
http://dx.doi.org/10.1038/s41467-021-27399-x