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Multi-omic analysis of selectively vulnerable motor neuron subtypes implicates altered lipid metabolism in ALS

Amyotrophic lateral sclerosis (ALS) is a devastating disorder in which motor neurons degenerate, the causes of which remain unclear. In particular, the basis for selective vulnerability of spinal motor neurons (sMNs) and resistance of ocular motor neurons (oMNs) to degeneration in ALS has yet to be...

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Detalles Bibliográficos
Autores principales: Lee, Hojae, Lee, Jae Jin, Park, Na Young, Dubey, Sandeep Kumar, Kim, Taeyong, Ruan, Kai, Lim, Su Bin, Park, Seong-Hyun, Ha, Shinwon, Kovlyagina, Irina, Kim, Kyung-tai, Kim, Seongjun, Oh, Yohan, Kim, Hyesoo, Kang, Sung-Ung, Song, Mi-Ryoung, Lloyd, Thomas E., Maragakis, Nicholas J., Hong, Young Bin, Eoh, Hyungjin, Lee, Gabsang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639773/
https://www.ncbi.nlm.nih.gov/pubmed/34782793
http://dx.doi.org/10.1038/s41593-021-00944-z