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Multi-omic analysis of selectively vulnerable motor neuron subtypes implicates altered lipid metabolism in ALS
Amyotrophic lateral sclerosis (ALS) is a devastating disorder in which motor neurons degenerate, the causes of which remain unclear. In particular, the basis for selective vulnerability of spinal motor neurons (sMNs) and resistance of ocular motor neurons (oMNs) to degeneration in ALS has yet to be...
Autores principales: | Lee, Hojae, Lee, Jae Jin, Park, Na Young, Dubey, Sandeep Kumar, Kim, Taeyong, Ruan, Kai, Lim, Su Bin, Park, Seong-Hyun, Ha, Shinwon, Kovlyagina, Irina, Kim, Kyung-tai, Kim, Seongjun, Oh, Yohan, Kim, Hyesoo, Kang, Sung-Ung, Song, Mi-Ryoung, Lloyd, Thomas E., Maragakis, Nicholas J., Hong, Young Bin, Eoh, Hyungjin, Lee, Gabsang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639773/ https://www.ncbi.nlm.nih.gov/pubmed/34782793 http://dx.doi.org/10.1038/s41593-021-00944-z |
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