O-GlcNAcylation of Sox2 at threonine 258 regulates the self-renewal and early cell fate of embryonic stem cells

Sox2 is a core transcription factor in embryonic stem cells (ESCs), and O-GlcNAcylation is a type of post-translational modification of nuclear-cytoplasmic proteins. Although both factors play important roles in the maintenance and differentiation of ESCs and the serine 248 (S248) and threonine 258...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Dong Keon, Lee, Jang-Seok, Lee, Eun Young, Jang, Hansol, Han, Suji, Kim, Hee Yeon, Hwang, In-Young, Choi, Ji-Woong, Shin, Hyun Mu, You, Hye Jin, Youn, Hong-Duk, Jang, Hyonchol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639819/
https://www.ncbi.nlm.nih.gov/pubmed/34819616
http://dx.doi.org/10.1038/s12276-021-00707-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639819/
https://www.ncbi.nlm.nih.gov/pubmed/34819616
http://dx.doi.org/10.1038/s12276-021-00707-7

Ejemplares similares