Antibody or Anybody? Considering the Role of MRGPRX2 in Acute Drug-Induced Anaphylaxis and as a Therapeutic Target

Acute anaphylaxis to small molecule drugs is largely considered to be antibody-mediated with immunogloblin E (IgE) and mast cell activation being key. More recently, a role for drug-reactive immunoglobulin G (IgG) with neutrophil activation has also been suggested, at least in reactions to neuromusc...

Descripción completa

Detalles Bibliográficos
Autores principales: Mackay, Graham A., Fernandopulle, Nithya A., Ding, Jie, McComish, Jeremy, Soeding, Paul F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639860/
https://www.ncbi.nlm.nih.gov/pubmed/34867939
http://dx.doi.org/10.3389/fimmu.2021.688930

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639860/
https://www.ncbi.nlm.nih.gov/pubmed/34867939
http://dx.doi.org/10.3389/fimmu.2021.688930

Ejemplares similares