Foot-and-Mouth Disease Virus 3C Protease Antagonizes Interferon Signaling and C142T Substitution Attenuates the FMD Virus

3C protease (3C(pro)), a chymotrypsin-like cysteine protease encoded by the foot-and-mouth disease virus (FMDV), plays an essential role in processing the FMDV P1 polyprotein into individual viral capsid proteins in FMDV replication. Previously, it has been shown that 3C(pro) is involved in the bloc...

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Detalles Bibliográficos
Autores principales: Ekanayaka, Pathum, Shin, Sung Ho, Weeratunga, Prasanna, Lee, Hyuncheol, Kim, Tae-Hwan, Chathuranga, Kiramage, Subasinghe, Ashan, Park, Jong-Hyeon, Lee, Jong-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639872/
https://www.ncbi.nlm.nih.gov/pubmed/34867853
http://dx.doi.org/10.3389/fmicb.2021.737031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639872/
https://www.ncbi.nlm.nih.gov/pubmed/34867853
http://dx.doi.org/10.3389/fmicb.2021.737031

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