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Optimization of entrapment efficiency and release of clindamycin in microsponge based gel

The aim of the present study was to formulate clindamycin (CLN) as a microsponge based gel to release the drug in a controlled manner and reduce the side effects in the treatment of acne. Since this method requires poor water solubility of the drug to be loaded in particles, therefore, conversion of...

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Detalles Bibliográficos
Autores principales: KHATTAB, ALAA, Nattouf, Abdulhakim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639917/
https://www.ncbi.nlm.nih.gov/pubmed/34857863
http://dx.doi.org/10.1038/s41598-021-02826-7