Regulation of the EphA2 receptor intracellular region by phosphomimetic negative charges in the kinase-SAM linker

Eph receptor tyrosine kinases play a key role in cell-cell communication. Lack of structural information on the entire multi-domain intracellular region of any Eph receptor has hindered understanding of their signaling mechanisms. Here, we use integrative structural biology to investigate the struct...

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Detalles Bibliográficos
Autores principales: Lechtenberg, Bernhard C., Gehring, Marina P., Light, Taylor P., Horne, Christopher R., Matsumoto, Mike W., Hristova, Kalina, Pasquale, Elena B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639986/
https://www.ncbi.nlm.nih.gov/pubmed/34857764
http://dx.doi.org/10.1038/s41467-021-27343-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8639986/
https://www.ncbi.nlm.nih.gov/pubmed/34857764
http://dx.doi.org/10.1038/s41467-021-27343-z

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