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GlomSpheres as a 3D co-culture spheroid model of the kidney glomerulus for rapid drug-screening

The glomerulus is the filtration unit of the kidney. Injury to any component of this specialised structure leads to impaired filtration and eventually fibrosis and chronic kidney disease. Current two and three dimensional (2D and 3D) models that attempt to recreate structure and interplay between gl...

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Detalles Bibliográficos
Autores principales: Tuffin, Jack, Chesor, Musleeha, Kuzmuk, Valeryia, Johnson, Tim, Satchell, Simon C., Welsh, Gavin I., Saleem, Moin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640035/
https://www.ncbi.nlm.nih.gov/pubmed/34857869
http://dx.doi.org/10.1038/s42003-021-02868-7