Single-cell transcriptional profiling of splenic fibroblasts reveals subset-specific innate immune signatures in homeostasis and during viral infection

Our understanding of the composition and functions of splenic stromal cells remains incomplete. Here, based on analysis of over 20,000 single cell transcriptomes of splenic fibroblasts, we characterized the phenotypic and functional heterogeneity of these cells in healthy state and during virus infe...

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Detalles Bibliográficos
Autores principales: Pezoldt, Joern, Wiechers, Carolin, Erhard, Florian, Rand, Ulfert, Bulat, Tanja, Beckstette, Michael, Brendolan, Andrea, Huehn, Jochen, Kalinke, Ulrich, Mueller, Mathias, Strobl, Birgit, Deplancke, Bart, Čičin-Šain, Luka, Sitnik, Katarzyna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640036/
https://www.ncbi.nlm.nih.gov/pubmed/34857864
http://dx.doi.org/10.1038/s42003-021-02882-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640036/
https://www.ncbi.nlm.nih.gov/pubmed/34857864
http://dx.doi.org/10.1038/s42003-021-02882-9

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