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Single-cell transcriptional profiling of splenic fibroblasts reveals subset-specific innate immune signatures in homeostasis and during viral infection
Our understanding of the composition and functions of splenic stromal cells remains incomplete. Here, based on analysis of over 20,000 single cell transcriptomes of splenic fibroblasts, we characterized the phenotypic and functional heterogeneity of these cells in healthy state and during virus infe...
Autores principales: | Pezoldt, Joern, Wiechers, Carolin, Erhard, Florian, Rand, Ulfert, Bulat, Tanja, Beckstette, Michael, Brendolan, Andrea, Huehn, Jochen, Kalinke, Ulrich, Mueller, Mathias, Strobl, Birgit, Deplancke, Bart, Čičin-Šain, Luka, Sitnik, Katarzyna M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640036/ https://www.ncbi.nlm.nih.gov/pubmed/34857864 http://dx.doi.org/10.1038/s42003-021-02882-9 |
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