Fluorinated rhamnosides inhibit cellular fucosylation

The sugar fucose is expressed on mammalian cell membranes as part of glycoconjugates and mediates essential physiological processes. The aberrant expression of fucosylated glycans has been linked to pathologies such as cancer, inflammation, infection, and genetic disorders. Tools to modulate fucose...

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Detalles Bibliográficos
Autores principales: Pijnenborg, Johan F. A., Rossing, Emiel, Merx, Jona, Noga, Marek J., Titulaer, Willem H. C., Eerden, Nienke, Veizaj, Raisa, White, Paul B., Lefeber, Dirk J., Boltje, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640046/
https://www.ncbi.nlm.nih.gov/pubmed/34857733
http://dx.doi.org/10.1038/s41467-021-27355-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640046/
https://www.ncbi.nlm.nih.gov/pubmed/34857733
http://dx.doi.org/10.1038/s41467-021-27355-9

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