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Multiscale interactome analysis coupled with off-target drug predictions reveals drug repurposing candidates for human coronavirus disease

The COVID-19 pandemic has highlighted the urgent need for the identification of new antiviral drug therapies for a variety of diseases. COVID-19 is caused by infection with the human coronavirus SARS-CoV-2, while other related human coronaviruses cause diseases ranging from severe respiratory infect...

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Detalles Bibliográficos
Autores principales: Sugiyama, Michael G., Cui, Haotian, Redka, Dar’ya S., Karimzadeh, Mehran, Rujas, Edurne, Maan, Hassaan, Hayat, Sikander, Cheung, Kyle, Misra, Rahul, McPhee, Joseph B., Viirre, Russell D., Haller, Andrew, Botelho, Roberto J., Karshafian, Raffi, Sabatinos, Sarah A., Fairn, Gregory D., Madani Tonekaboni, Seyed Ali, Windemuth, Andreas, Julien, Jean-Philippe, Shahani, Vijay, MacKinnon, Stephen S., Wang, Bo, Antonescu, Costin N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640055/
https://www.ncbi.nlm.nih.gov/pubmed/34857794
http://dx.doi.org/10.1038/s41598-021-02432-7