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Oxidative damage-induced hyperactive ribosome biogenesis participates in tumorigenesis of offspring by cross-interacting with the Wnt and TGF-β1 pathways in IVF embryos

In vitro fertilization (IVF) increases the risk of tumorigenesis in offspring. The increased oxidative damage during IVF may be involved in tumor formation. However, the molecular mechanisms underlying this phenomenon remain largely unclear. Using a well-established model of oxidatively damaged IVF...

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Detalles Bibliográficos
Autores principales: Huang, Yue, Li, Zhiling, Lin, En, He, Pei, Ru, Gaizhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640061/
https://www.ncbi.nlm.nih.gov/pubmed/34848840
http://dx.doi.org/10.1038/s12276-021-00700-0