Cargando…
Oxidative damage-induced hyperactive ribosome biogenesis participates in tumorigenesis of offspring by cross-interacting with the Wnt and TGF-β1 pathways in IVF embryos
In vitro fertilization (IVF) increases the risk of tumorigenesis in offspring. The increased oxidative damage during IVF may be involved in tumor formation. However, the molecular mechanisms underlying this phenomenon remain largely unclear. Using a well-established model of oxidatively damaged IVF...
Autores principales: | Huang, Yue, Li, Zhiling, Lin, En, He, Pei, Ru, Gaizhen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640061/ https://www.ncbi.nlm.nih.gov/pubmed/34848840 http://dx.doi.org/10.1038/s12276-021-00700-0 |
Ejemplares similares
-
High Dosages of Equine Chorionic Gonadotropin Exert Adverse Effects on the Developmental Competence of IVF-Derived Mouse Embryos and Cause Oxidative Stress-Induced Aneuploidy
por: Lin, En, et al.
Publicado: (2021) -
The role of bystin in embryo implantation and in ribosomal biogenesis
por: Fukuda, M. N., et al.
Publicado: (2007) -
Elevated RIF1 participates in the epigenetic abnormalities of zygotes by regulating histone modifications on MuERV-L in obese mice
por: Huang, Jiliang, et al.
Publicado: (2022) -
40S Ribosome Biogenesis Co-Factors Are Essential for Gametophyte and Embryo Development
por: Missbach, Sandra, et al.
Publicado: (2013) -
AMPK Activity Contributes to G2 Arrest and DNA Damage Decrease via p53/p21 Pathways in Oxidatively Damaged Mouse Zygotes
por: He, Pei, et al.
Publicado: (2020)