TERT genetic variability and telomere length as factors affecting survival and risk in acute myeloid leukaemia

Acute myeloid leukaemia (AML) is a neoplasm of immature myeloid cells characterized by various cytogenetic alterations. The present study showed that in addition to the FLT3-ITD and NPM1 mutation status, telomere length (TL) and telomerase reverse transcriptase (TERT) gene polymorphisms may affect r...

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Detalles Bibliográficos
Autores principales: Dratwa, Marta, Wysoczańska, Barbara, Butrym, Aleksandra, Łacina, Piotr, Mazur, Grzegorz, Bogunia-Kubik, Katarzyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640063/
https://www.ncbi.nlm.nih.gov/pubmed/34857839
http://dx.doi.org/10.1038/s41598-021-02767-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8640063/
https://www.ncbi.nlm.nih.gov/pubmed/34857839
http://dx.doi.org/10.1038/s41598-021-02767-1

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